Regression of central giant cell granuloma by a combination of imatinib and interferon: a case report

Authors
Publication date 2009
Journal British Journal of Oral & Maxillofacial Surgery
Volume | Issue number 47 | 1
Pages (from-to) 59-61
Organisations
  • Faculty of Dentistry (ACTA)
  • Faculty of Medicine (AMC-UvA)
Abstract Central giant cell granuloma is a benign lesion of the jaws which is sometimes aggressive locally. The most common treatment is curettage which has a high recurrence rate. particularly, in more aggressive lesions. Other treatments Such as interferon (IFN) and calcitonin have been described. We report a patient with Stickler syndrome and in aggressive central giant cell granuloma in the mandible. Initial treatment with calcitonin was not successful. A combination of IFN and imatinib, given for 9 months, initiated regression of the lesion that Continued after treatment had ceased.
Document type Article
Language English
Published at https://doi.org/10.1016/j.bjoms.2008.05.013
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