Ritonavir

Thesis

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Titlepage

Table of Contents

Chapter 1 Introduction

Chapter 2 The effect of treatment intensification in HIV-infection. A study comparing treatment with ritonavir/saquinavir and ritonavir/saquinavir/stavudine

Chapter 3 Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine

Chapter 4 Increasing CSF chemokine concentrations despite undetectable CSF HIV-RNA in HIV-1 infected patients on antiretroviral therapy

Chapter 5 Decreased exposure to saquinavir in HIV-1-infected patients after long term antiretroviral therapy including ritonavir and saquinavir

Chapter 6 Stavudine concentrations in the plasma and cerebrospinal fluid: A possible interaction with ritonavir and/or indinavir?

Chapter 7 Quality of life in asymptomatic- and symptomatic HIV infected patients in a trial of ritonavir/saquinavir therapy

Chapter 8 Adherence over 48 weeks in an antiretroviral clinical trial: variable within patients, affected by toxicities and independently predictive of virological response

Chapter 9 Risk factors for hepatotoxicity in HIV-1 infected patients receiving ritonavir and saquinavir with or without stavudine

Chapter 10 Increased risk of lipodystrophy when including nucleoside analogue reverse transcriptase inhibitors in the treatment of HIV-1 infection with protease inhibitors: results from a randomised controlled trial

Chapter 11 General discussion

Chapter 12 Summary

Chapter 13 Nederlandse samenvatting

Chapter 14 Over Prometheus

Dankwoord

Publications

Curriculum vitae

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