Molecular mechanisms in colon cancer

Authors	J.C.H. Hardwick
Supervisors	S.J.H. van Deventer
Cosupervisors	M.P. Peppelenbosch
Award date	25-09-2002
ISBN	9090160957 9789090160955
Number of pages	185
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: CLDO
Downloads	Thesis Cover Titlepage Contents Chapter I Introduction Chapter II Leptin is a growth factor for colonic epithelial cells Chapter III NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps Chapter IV Aspirin and Indomethacin act directly on the Wnt/β-catenin pathway Chapter V DNA array analysis into the effects of Aspirin on colon cancer cells: Involvement of Rac1 Chapter VI Bone Morphogenetic Protein 2 is expressed by, and acts upon, mature epithelial cells in the colon Chapter VII Sonic Hedgehog regulates gastric gland morphogenesis in man and mouse Chapter VIII Sonic Hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract Chapter IX Indian Hedgehog is a novel regulator of colonic epithelial homeostasis in the adult rat and human Chapter X Summary Chapter XI Summary in Dutch Acknowledgements References Cover
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