CD44, TLR4, TREM-1/DAP12 in renal injury, inflammation and fibrosis

Authors	E. Rampanelli
Supervisors	S. Florquin
Cosupervisors	J.C. Leemans
Award date	22-05-2014
ISBN	9789461824349
Number of pages	191
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title pages Contents Chapter 1: General introduction & Outline of this thesis Chapter 2: CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction Chapter 3: TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury Chapter 4: Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy Chapter 5: CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy Chapter 6: Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy Chapter 7: Summary and discussion Nederlandse samenvatting List of abbreviations Publications Curriculum vitae Acknowledgements
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