In vitro studies on radiation effects and radiosensitization: HDR vs LDR and cytotoxic agents

Authors	N. Castro Kreder
Supervisors	D. González González
Cosupervisors	J. Haveman
Award date	16-06-2004
ISBN	9064649642 9789064649646
Number of pages	195
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: GEMO
Downloads	Thesis Cover Titlepage Contents Chapter One: General Introduction Chapter Two: Chromosomic aberrrations detected by FISH and correlation with cell survival after irradiation at various dose-rates and after bromodeoxyuridine radiosensitization Chapter Three: Colour junctions as predictions of radiosensitivity: X-irradiation combined with gemcitabine in a lung carcinoma cell line Chapter Four: Enhancement of effects of irradiation by gemcitabine in a glioblastoma cell line and cell line spheroids Chapter Five: Sensitivity to ionizing radiation and chemotherapeutic agents in Gemicitabine-resistant human tumor cell lines Chapter Six: Effects of Gemcitabine on cell survival and chromosome aberrations after pulsed low dose rate irradiation Chapter Seven: Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation Chapter Eight: Cellular response to pulsed low dose rate irradiation in X-ray sensitive hamster mutant cell lines Chapter Nine: Summary, Conclusions and Future Directions Nederlands Samenvatting Curriculum Vitae Dankwoord Cover
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