Selective para-C–H Alkynylation of Aniline Derivatives via Pd/S,O-Ligand Catalysis

Open Access
Authors
Publication date 16-02-2022
Journal Chemistry - A European Journal
Article number e202104107
Volume | Issue number 28 | 9
Number of pages 4
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract Herein, we report a nondirected para-selective C−H alkynylation of aniline derivatives by a Pd/S,O-ligand-based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have been also demonstrated.
Document type Article
Note With supplementary file.
Language English
Published at https://doi.org/10.1002/chem.202104107
Other links https://www.scopus.com/pages/publications/85122732752
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