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Mitochondria in neutrophil apoptosis

Open Access
Authors
  • B.J. van Raam
Supervisors
  • T.W. Kuijpers
  • D. Roos
Cosupervisors
  • A.J. Verhoeven
Award date 20-01-2009
Number of pages 141
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Language English
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Thesis
Front cover
Title pages
Contents
Preface: Outline and scope of the thesis
Chapter 1: Introduction : mitochondria in neutrophil apoptosis
Chapter 2: Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation
Chapter 3: Mitochondria-derived reactive oxygen species are required for the prosurvival effect of tumor necrosis-factor-α in human neutrophils
Chapter 4: Neutropenia and mitochondrial defects in Barth syndrome
Chapter 5: Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3
Chapter 6: Changes in gene expression of granulocytes during in vivo G-CSF/ dexamethasone mobilization for transfusion purposes
Chapter 7: Temporal and spatial regulation of Bfl-1 expression during the later stages of neutrophil apoptosis
Conclusion: Summary, discussion and prospective
Appendix: List of common abbreviations
Samenvatting in het Nederlands
Acknowledgements/dankwoord
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