Organocatalytic Fluorogenic Synthesis of Chromenes
| Authors | |
|---|---|
| Publication date | 05-2017 |
| Journal | Journal of fluorescence |
| Volume | Issue number | 27 | 3 |
| Pages (from-to) | 1141-1147 |
| Organisations |
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| Abstract | Two fluorescent derivatives of 2-amino-3-carbonitrile-4H-chromene were synthesized by means of a fluorogenic Michael addition of dimedone to dicyano alkene labeled BODIPY derivatives. Different organocatalysts were used in different conditions to obtain compounds 3 and 4 in good yield (up to 65% and 85 and moderate enantiomeric excess (51% and 41% ee, respectively). This work provides the first example of an enantioselective organocatalytic conversion combined with fluorogenesis. |
| Document type | Article |
| Note | With supplementary file |
| Language | English |
| Published at | https://doi.org/10.1007/s10895-017-2049-7 |
| Downloads |
10.1007_s10895-017-2049-7
(Final published version)
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| Supplementary materials | |
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