K-ras and p53 in cancer of the pancreas and extrahepatic biliary tract

Thesis

Cover

Titlepage

Contents

General Introduction

Chapter 1. K-ras Mutations in the Duodenal Fluid of Patients with Pancreatic Carcinoma

Chapter 2. The Potential Diagnostic Use of K-ras Codon 12 and p53 Alterations in Brush Cytology from the Pancreatic Head Region

Chapter 3. The Clinical Value of K-ras Codon 12 Analysis and Endobiliary Brush Cytology for the Diagnosis of Malignant Extrahepatic Bile Duct Stenosis

Chapter 4. Diagnostic p53 Immunostaining of Endobiliary Brush Cytology; Preoperative Cytology Compared to Surgical Specimen

Chapter 5. Can K-ras Codon 12 Mutations Be Used to Distinguish Benign Bile Duct Proliferations from Metastases in the Liver? A Molecular Analysis of 101 Liver Lesions from 93 Patients

Chapter 6. Alterations of the p53 Tumor Suppressor Gene and K-ras Oncogene in Perihilar Cholangixarcinomas from a High-Incidence Area

Chapter 7. K-ras Oncogene Mutations in Osteoclast-like Giant Cell Tumors of the Pancreas and Liver. Genetic Evidence to Support Origin from the Duct Epithelium

Summary

Samenvatting

Figures

Dankwoord

Curriculum Vitae

Cover