Modulation of fibroblast activity by collagens

Thesis

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Titlepage

Contents

1: General Introduction

2: Collagen breakdown in soft connective tissue explants is associated with the level of active gelatinase A (MMP-2) but not with collagenase

3: Matrix metalloproteinases modulate release and activation of gelatinase A (MMP-2) in soft connective tissue

4: Collagen type I. Ill and V differently modulate production and activation of matrix metalloproteinase I (MMP-I) and matrix metalloproteinase 2 (MMP-2) by periodontal ligament fibroblasts

5: Collagen types I, III and V differently modulate synthesis and activation of MMPs by periosteal, gingival and periodontal ligament fibroblasts

6. Synthesis of DNA by fibroblasts is modulated by the collagen types I, III and V

7: General discussion

8: Summary

9: Samenvatting

Dankwoord

Curriculum vitae

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